This video from Steely Library at Northern Kentucky University defines and provides examples of evidence-based practice. (CC-BY-NC 4.0)
Formulating a strong clinical question is the first step in the research process. PICO is a way of building clinical research questions that allow you to focus your research, and to create a query that better matches most medical databases.
Example: In a (describe patient) can (intervention A) affect (outcome) compared with (intervention B)?